In this Nov. 6, 2000, photo, then-U.S. Senate candidate first lady Hillary Rodham Clinton meets Rob Buck of the 10,000 Maniacs during a campaign stop in Buffalo, N.Y. No other first lady had been elected to public office when she won the 2000 election for Senate in New York. And she was the first woman to serve as a senator from New York, followed when she left office by the second, Kirsten Gillibrand. Hillary Clinton has officially become the first woman to be the presidential nominee of a major U.S. political party. (AP Photo/David Duprey)

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